Microbiome restoration using beneficial microorganisms for corals (BMCs) comprise a promisingstrategy to help corals cope with anthropogenic stressors. However, there is limited knowledge on theuptake of BMCs by nontarget animals, especially sponges. This study explores whether sponges canacquire BMCs upon direct application and whether inoculations affect sponge health. A 4-week fieldexperiment applying BMCs to Stylissa carteri and Callyspongia crassa assessed three conditions: noinoculation, and BMCs inoculation once and thrice a week. BMC-related strains were naturally presentin the seawater and the microbiome of S. carteri. These strains were enriched in response to theinoculation only in the S. carteri microbiome. Microbiomes of both sponges were restructured;sponges were visually healthy and efficiently pumped water at the end of the experiment. These resultssuggest that sponges can be enriched with BMC-related strains, and that BMC application on nearbycorals is unlikely to negatively affect sponge health.